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Child & Adolescent Health
11th Mar, 2026
The Lancet
Pinhas-Hamiel O, Simchoni M, Derazne E, et al. Delayed puberty and early-onset type 2 diabetes risk: a nationwide cohort study of male adolescents in Israel. Lancet Child Adolesc Health 2026; 10: 103–10—In this Article, the p values in table 1 have been corrected along with the p value at the end of the first paragraph in the Results section. Two mean ages in the Findings section of the Summary have also been corrected. These corrections have been made to the online version as of Feb 12, 2026.
Morgan J. Chandy John: Using his heart and head for change that matters. Lancet Child Adolesc Health 2026; 10: 80—In this Reflections, the place of Chandy John's training has been corrected to the University of Michigan. This correction has been made to the online version as of Feb 12, 2026.
Chellappa SL. Addressing multiple neurodivergent identities in clinical and research settings. Lancet Child Adolesc Health 2025; 9: 5–6—In this Comment, the fourth sentence of the first paragraph should read “Neurodivergent identities are rarely singular, for example 37–85% of autistic children also have ADHD symptoms.3” and the fourth sentence of the second paragraph should read “Moreover, individuals who are autistic and ADHD (AuADHD) often have their diagnoses at a later stage in their life”.
Despite decades of research, adolescent health studies still rarely engage young people directly. Major reviews consistently identify a critical gap: there are very few formal training pathways to prepare young people for participation in research, beyond as the ones being studied. As co-author Sara, who joined the Youth Well Lab at age 16 years as youth advisor in 2019, said: “We want to be involved in research that is about us, but the area seems so inaccessible and unapproachable to many our age that we remain disconnected rather than engaged”.
In paediatrics, “more trials have been done over the last ten years, but we have struggled with transparency and clarity, and sometimes with the quality because they are not always asking the questions and measuring the outcomes that are relevant for the children and their families”, explains paediatrician Martin Offringa (The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada), Principal Investigator for the paediatric-specific extensions of the SPIRIT and CONSORT reporting guidelines project.
Globally, 3·1 million children are hospitalised with respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) annually.1 The incidence of RSV LRTI per 1000 children per year in upper-middle-income countries (130·8; uncertainty range [UR] 56·8–300·8) and lower-middle-income countries (106; UR 63·5–177) is similar to, if not higher than, that of low-income countries (75·9; UR 42·7–134·7).2
Sustained and equitable improvements in the health and wellbeing of populations globally, particularly for children and adolescents, will be fundamentally shaped by the ability of the global clinical trial community to deliver high-quality, trustworthy evidence. Such evidence, and how it is presented, is essential to inform guidelines, policy, and investment. For this reason, the importance of reporting standards for how health research is conceptualised and implemented, and findings described, has never been greater.
Adolescent HIV prevention is at a crucial point. Despite advances in diagnostics, treatment, and service delivery, few approaches effectively reach adolescents before sexual debut.1 School, community, and health-system programmes have strengthened knowledge and access to services, yet many young people still enter their first sexual experiences without the skills or protection needed to reduce HIV risk. Early adolescence remains a pivotal but underserved stage,1 with limited interventions designed for this period and few assessed over the long term.
In the UK, it is compulsory to stay in education or training until age 18 years. However, recent funding changes for post-16 programmes in England, Northern Ireland, and Wales require at least grade 4 (equivalent to grade C in the previous grading system) in English and Maths General Certificates of Secondary Education (GCSEs) to progress to further study or training. GCSEs are exams sat by students aged 15–16 years at the end of secondary education. This requirement has resulted in more students having to resit exams, sometimes repeatedly, although pass rates among resit candidates remain low.
Much uncertainty remains in the evidence base for child and adolescent health. Not only is the quality of clinical trials involving neonates, children, and adolescents inconsistent; in numbers, they lag behind adult trials. The unique needs of paediatric populations are often inadequately considered and described, partly because no specific reporting guidelines exist. Published in The Lancet Child & Adolescent Health, the CONSORT-Children and Adolescents (CONSORT-C) extension guideline for trial reporting—alongside its companion SPIRIT-C guideline for trial protocols—marks a new era for child and adolescent health research.
Surgery
Journal of the American Medical Association
This Perspective discusses the limitations of reliable assessment of consciousness in critically ill, behaviorally unresponsive patients in light of recent situations in which such patients exhibited signs of consciousness moments before initiation of organ recovery surgery.
This Viewpoint discusses the need to frame delays and failures in access to health care as patient safety events and to apply high-reliability organization principles to these access-related events to incorporate systematic analysis, leadership attention, and organizational accountability.
This survey study examines responses from surgeon-parents to analyze the prevalence of obstetric complications among childbearing surgeons and childbearing partners of surgeons, identify occupational risk factors, and explore the respondents’ lived experiences.
Despite a majority of surgeons having children and many institutions having policies in place intended to support pregnant surgeons, obstetric complications remain high for both childbearing surgeons and childbearing partners of surgeons. Halix et al provide a first-of-its-kind survey of both childbearing surgeons as well as surgeons whose partners gave birth to assess obstetric complication rates, identify risk factors among the groups, and assess the cultural context of these complications related to the field of surgery. Despite a majority of surgeons having children and many institutions having policies in place intended to support pregnant surgeons, obstetric complications remain high for both childbearing surgeons and childbearing partners of surgeons. Halix et al provide a first-of-its-kind survey of both childbearing surgeons as well as surgeons whose partners gave birth to assess obstetric complication rates, identify risk factors among the groups, and assess the cultural context of these complications related to the field of surgery.
Diabetes & Endocrinology
Breast cancer risk is a central concern in shared decision-making when considering menopausal hormone treatment (MHT). Women spend approximately 40% of their lives in menopause, and climacteric symptoms can substantially impair quality of life. MHT is the most effective strategy to treat climacteric symptoms. MHT can consist of the administration of oestrogen only in women who have undergone hysterectomy or a combined treatment of oestrogen and progestogen in women with a uterus. The risk of breast cancer associated with MHT varies with both the individual's baseline risk of breast cancer and the type of treatment.
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