PMC recently redesigned its URL format to allow for easier usability as well as consistency across the NCBI site. To implement this change, we moved the previous site, www.pubmedcentral.nih.gov, into the NCBI domain as a sub-site. You can now access the PMC home page at https://www.ncbi.nlm.nih.gov/pmc. The primary advantage of the new format is to enable the PMC site to become more fully integrated with other NCBI resources. The new URLs are also more user-friendly—they no longer include technology-driven terminology, such as CGI script names and file extensions (Figure 1). Figure 1 - Old URL for Journal Page with CGI Script Name Instead, note that after the NCBI/PMC address, the URL first identifies the type of resource, e.g., the PMC journal list, with subsequent identification for a particular subset of that resource—in this case, the journal number (Figure 2). Figure 2 - New URL for Journal Page with Journal Number Additionally, you will have greater flexibility in accessing particular types of material because, in a number of cases, more than one URL can be used for the same resource. In these instances, one URL is considered to be canonical, or primary; however, using any of the ancillary URLs for that resource will redirect you back to the canonical one. For example (see Figure 3), although the first URL, which represents the PMCID, is considered to be the canonical URL, you may also access the article by using other identifiers, such as the pmid, doi, or the issn-volume-issue-page (ivip). Figure 3 - Canonical and Ancillary URLs for the Same Full-Text Article Finally, with the roll-out of these more stable and standardized URLs, as in the table below (Figure 4), you will also find it easier to modify the web addresses in your browser. Note that the canonical URL is given first and is in bold; the ancillary URLs are listed below it. Figure 4 - Table Display of all New URLs Although the new URLs are firmly in place, please also note that we haven't completely discarded the old to bring in the new. If you do use an old URL, it's not a problem. Your browser will be redirected to the new location.