Search Medical Journals & Research Articles

Expiratory Central Airway Collapse

A woman with asthma and obstructive sleep apnea presented with a 1-month history of worsening dyspnea and dry cough. CT of the chest showed anterior bowing of the posterior wall of the intrathoracic trachea during expiration.

The Eyes Have It

A 47-year-old man was brought to the ED by EMS after being found dyspneic in his car. He reported having been drinking for 6 hours before presentation. He noted a sensation of tongue swelling and difficulty breathing.

Good Compressions

Faced with a young woman whose seizures, of untraceable cause, can’t be stopped by the medical team, a medical student viscerally learns the limits to what can be accomplished by pushing harder.

High-Dose Influenza Vaccine Effectiveness against Hospitalization in Older Adults

Among adults 65 years of age or older, a high-dose influenza vaccine did not result in a significantly lower incidence of hospitalization for influenza or pneumonia than a standard-dose vaccine.

High-Dose Influenza Vaccine to Reduce Hospitalizations

In adults 65 to 79 years of age, there appeared to be fewer hospitalizations for influenza or pneumonia with high-dose influenza vaccine than with the standard dose, with a similar incidence of serious adverse events.

Where Do I Put This?

Grieving over a beloved patient who’d invited her into the private, sacred space of her planned day of death, a palliative care physician finds it hard to switch gears as she sits in a PTA meeting.

RSV Prefusion F Vaccine for Prevention of Hospitalization in Older Adults

In this open-label, randomized trial, the RSV vaccine reduced the incidence of hospitalization for RSV-related respiratory tract disease as compared with no vaccine among adults 60 years of age or older.

Medical Management and Revascularization for Asymptomatic Carotid Stenosis

In high-grade asymptomatic carotid stenosis, addition of stenting to medical therapy led to a lower risk of stroke over a 4-year period. Endarterectomy did not lead to a significant benefit.

Subretinal Photovoltaic Implant to Restore Vision in Geographic Atrophy Due to AMD

In persons with geographic atrophy due to age-related macular degeneration, a neurostimulation system composed of glasses, a processor, and a subretinal implant restored central vision and significantly improved visual acuity.

Case 4-2026: An 80-Year-Old Woman with Cough and Hypoxemia

An 80-year-old woman was admitted to the hospital because of cough and hypoxemia (oxygen saturation, 83%). CT of the chest showed diffuse ground-glass opacities in both lungs. A diagnosis was made.

Seeing It Through — Lessons from a Retinal Stroke Trial

The retina is a specialized patch of central nervous system tissue located at the back of the eye. When the principal source of oxygen and metabolic substrates to the retina — the central retinal artery — is occluded, rapid retinal cell death and loss of visual function ensue. This acute… The retina is a specialized patch of central nervous system tissue located at the back of the eye. When the principal source of oxygen and metabolic substrates to the retina — the central retinal artery — is occluded, rapid retinal cell death and loss of visual function ensue. This acute…

A Randomized Trial of Tenecteplase in Acute Central Retinal Artery Occlusion

In acute central retinal artery occlusion treated within 4.5 hours after onset, intravenous tenecteplase did not result in greater recovery of vision at 30 days than aspirin and was associated with serious safety concerns.

Secondary Prevention after Ischemic Stroke

After ischemic stroke, recurrence risk is reduced by identifying the stroke mechanism and targeting modifiable risk factors. Early diagnostic evaluation, prompt preventive therapy, and ongoing monitoring are central to care.

Case 7-2026: A 91-Year-Old Man with Left Knee Pain

A 91-year-old man with a history of bladder carcinoma and left total knee arthroplasty was evaluated because of left knee pain. A culture of synovial fluid showed no growth. A diagnosis was made.

Blood-Pressure Targets in Hypertension Management

This feature about blood-pressure targets to manage hypertension offers a case vignette accompanied by two essays, one recommending a systolic blood-pressure target of less than 120 mm Hg and the other supporting a target of less than 140 mm Hg.