

“I shouldn't be here”, said stand-up comedian Yvonne Hughes towards the start of her performance, before taking a step to her right. “I should be here instead”. The joke, which drew a suitably loud groan from her preview show's audience, epitomises the mix of comedy in Hughes' routine, juxtaposing the well-used phrase uttered by people who have defied doctors' expectations to survive, with a gag about not hitting the right mark on the stage. Hughes, 52, was diagnosed with cystic fibrosis when she was only a few months old, at a time when people with the condition were expected to only live into their early 20s.
Respiratory Medicine
|15th Jan, 2026
|The Lancet
Respiratory Medicine
|15th Jan, 2026
|The Lancet
Respiratory Medicine
|15th Jan, 2026
|The Lancet
Respiratory Medicine
|15th Jan, 2026
|The Lancet
Respiratory Medicine
|15th Jan, 2026
|The Lancet
Respiratory Medicine
|15th Jan, 2026
|The Lancet
Respiratory Medicine
|15th Jan, 2026
|The Lancet