[Articles] D-Dimer thresholds for diagnosis of pulmonary embolism based on a single question: is it the most likely diagnosis? A prospective, multicentre, open-label, single-arm interventional study

A global simplified strategy using a D-dimer threshold of 1000 ng/mL in patients for whom pulmonary embolism was not the most likely diagnosis, and an age-adjusted threshold for other patients, safely excluded the diagnosis. These findings indicate that this simplified strategy could safely reduce the use of chest imaging in the emergency department.