[Comment] Morphine for chronic breathlessness: time to say goodbye

The effect of chronic breathlessness on the lives of patients and their loved ones is tremendous, regardless of the underlying cause.1 Persistent breathlessness despite optimal treatment of the underlying disease is very common in chronic obstructive pulmonary disease (COPD), heart failure, cancer, and interstitial lung disease. Combined with the knowledge that the global burden of these diseases is still increasing,2 it seems nearly impossible to overstate the need for effective breathlessness treatments.