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Medical News
3rd Dec, 2025
phys.org
Eight out of 10 people in Spain admit to being satisfied with their jobs, according to a survey by the 40dB Institute. But what would happen if these same workers were asked about their emotions and experiences? What if they were asked to recall the last time they felt enthusiastic, joyful or fulfilled in response to a pleasant surprise at work?
A team of researchers from Academia Sinica and National Taiwan University has identified the Drosophila Cul2 substrate adaptor DmZer1 as a key regulator of protein quality control, acting at the intersection of two major cellular cleanup systems: autophagy and the ubiquitin-proteasome system. Interestingly, lowering DmZer1 levels activates the Cnc/Nrf2 stress-response pathway, which in turn strengthens the cell's ability to defend itself against oxidative stress.
A recent study published in Earth and Planetary Science Letters is the first to directly link earthquakes to climate change-induced glacial melt. Scientists analyzed 15 years of seismic activity in the Grandes Jorasses—a peak that is part of the Mont Blanc massif between Italy and France—to better understand this association. This massif is one of the more seismologically active areas in the region, and examining how climate change may affect earthquakes there could prove useful in preparing for them.
Some music is for grooving: It evokes spontaneous dancing, like head bopping, jumping, or arm swinging. Other music is for swaying, or for crying, or for slow dancing. Music makes people move, but whether musicians intentionally induce specific movements with their compositions, such as vertical bouncing or horizontal swaying, or what musical features would contribute to these distinctions, is more complex.
Despite being the third-largest producer and consumer of beer worldwide, Brazil depends almost entirely on hop imports. Less than 1% of the ingredient responsible for the bitterness, aroma, and flavor of beer is grown locally. However, a new project involving Brazilian scientists and producers in the Vale do Ribeira region of the state of São Paulo seeks to change this scenario. The project aims to make domestic hop production more efficient and viable while boosting the development of new bioproducts.
Farmers plant or preserve riparian buffers for various reasons, such as improving water quality, controlling erosion, or maintaining hunting habitat. Now, a new study from the University of Illinois Urbana-Champaign underscores the benefits of riparian buffers to terrestrial biodiversity, finding that for every 10% increase in forest cover, an additional species is present.
Regional Health – Europe
The Lancet
Significant regional differences in hospitalisation rates and risk-standardised mortality rates were observed among patients hospitalised for heart failure. Regional disparities in gross domestic product per capita may partly explain these differences. These results have clinical and policy implications, underscoring the need to consider socioeconomic determinants when analysing health outcomes and designing public policies aimed at reducing health inequalities. Our findings might be relevant to other European countries with similar public health systems.
Child & Adolescent Health
31st Dec, 2025
In the field of paediatrics, the concept of normal (ie, typical)—in contrast to different, special, deviant, delayed, or atypical—has imposed a problematic framework within which people view a child with an impairment. This binary perspective oversimplifies a complex, fluid, and dynamic process encompassing physical, behavioural, emotional, cognitive, social, and communicative development. Furthermore, this approach reinforces the notion of a singular normality, diminishing the value of any variation from this assumed (and usually poorly defined and naive) standard, in a way that speaks of ableism—the normative bias that a standard norm exists and anything other than this standard is inferior.
Each year, one billion children globally experience violence, which carries lifelong detrimental effects. In 2016, WHO and partners launched the INSPIRE Framework: seven strategies to end violence against children. A decade after INSPIRE's development, this systematic review updates its evidence base and assesses which interventions could be prioritised for implementation. This systematic review of systematic reviews searched 152 information sources from Jan 1, 2010, to May 15, 2023, to identify systematic reviews evaluating the effectiveness of policies or interventions in addressing violence against children.
Emotional distress among adolescents in most participating countries was higher in 2022 than in 2018, with disproportionate increases in the number of those reporting high degrees of distress. This pattern suggests a widening of vulnerabilities and highlights an urgent need for scalable and context-sensitive responses, such as strengthening school-based supports, integrating mental health into primary care, and expanding digital and community-based interventions.
CGF remains a leading factor associated with death and disability in children younger than 5 years, despite global attention and focused interventions to reduce the prevalence of associated CGF indicators. Our findings underscore the need for policies, strategies, and interventions that focus on all indicators of CGF to reduce its associated health burden.
Sampri A, Shi W, Bolton T, et al. Vascular and inflammatory diseases after COVID-19 infection and vaccination in children and young people in England: a retrospective, population-based cohort study using linked electronic health records. Lancet Child Adolesc Health 2025; 9: 837–47—In this Article, the fourth sentence of the final paragraph in the Results section should read “AERs were higher in the first versus second period of the COVID-19 pandemic …”. This correction has been made to the online version as of Nov 6, 2025
Ojha S, Mitchell EJ, Johnson MJ, et al. Full exclusively enteral fluids from day 1 versus gradual feeding in preterm infants (FEED1): an open-label, parallel-group, multicentre, randomised, superiority trial. Lancet Child Adolesc Health 2025; 9: 827–36—For this Article, the FEED1 collaborator list in the appendix has been updated and the corresponding page numbers in the text have been corrected. The title has also been corrected. These corrections have been made to the online version as of Dec 2, 2025.
The Lancet Child & Adolescent Health is proud to partner with Streetlights Uganda for the journal's cover art in 2026. Over the coming year, each issue will showcase art by a former street-connected young person. As apprentices of Streetlight Uganda's Mwalimu Mentorship Program [Mwalimu is Swahili for tutor], 12 children aged 7–20 years use art to express their personal reflections on one of two themes: “Nature as a refuge” and “Healing spaces”.
“Think about that for a second—in one of the richest countries on Earth, the most common thing that parents are asking for is a safe bed for their baby”, explained paediatrician Dr Guddi Singh during the first episode of Three Ages of Child, her three-part series broadcast on BBC Radio 4 in the UK. Exploring children's early years, school years, and adolescence, her series examined the underlying causes of the childhood illnesses she sees in her clinic. Singh began in Hartlepool, the town in northeast England where she grew up, with a visit to a Baby Bank, which not only provides families with essential items—such as the clothes, nappies, and beds requested by parents—but also a space for conversations to help tackle loneliness.
Medical Journal
15th Jan, 2026
Wiley
What's New: Drugs
FDA
Cardiology
Journal of the American Medical Association