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[Articles] Management and survival of patients with cancer of unknown primary discussed by a French national multidisciplinary tumour board: a retrospective analysis

Integration of clinical, pathological and molecular data within an expert MTB is feasible in a real-life setting, enables access to molecularly guided treatments and improves survival for a large proportion of CUP patients. Our findings highlight the benefits of dedicated MTB and reference centres to improve the management of CUP.

[Comment] Ending HIV transmission in Europe

Many European countries have managed to reduce HIV incidence tremendously over the past decades, yet declines have stalled, or even reversed, in many countries.1 By combining data from national HIV surveillance and population statistics, Jongen et al. provide a unique insight into the structural risk factors for HIV diagnosis in The Netherlands.2 HIV diagnoses were disproportionally found among individuals with a migrant background, and people with economic and mental health vulnerabilities. These data can help design tailored HIV treatment and prevention strategies to reach those at highest risk and ensure trends in incidence revert back to their downward trajectory.

[Articles] Suicide after involuntary psychiatric care: a nationwide cohort study in Sweden

We found substantial risk differences in distinct subgroups of IPC patients and an excess suicide risk among IPC patients compared to other clinical populations. These findings warrant further investigation as they could inform clinicians and policy makers regarding potential risk stratification, monitoring, and care. Preventing suicides after IPC should be a priority.

[Articles] Examination of self-harm clustering in adolescent peer networks: a nationwide registry cohort study in Finland

While we cannot rule out residual confounding, our findings suggest that self-harm may socially transmit within adolescent peer networks. The observed highest risk around age 16 suggests that external stressors associated with transitioning to new life stages at this age may moderate the impact of peer self-harm exposure. Prevention and intervention measures that consider possible peer influences on adolescents’ self-harming behaviour may help reduce the public health burden of self-harm.

[Articles] Brand-specific influenza vaccine effectiveness in three Nordic countries during the 2024–2025 season: a target trial emulation study based on registry data

Seasonal influenza vaccines moderately reduced the risk of severe outcomes in older adults. Efluelda Tetra and Fluad Tetra appeared to offer favourable protection in their respective target groups, supporting their use in the 2025/2026 season. Annual monitoring using Nordic registries is crucial for informing evidence-based vaccination strategies and regulatory decisions.

[Articles] Impact of cigarette prices and age-of-sale policies on smoking prevalence among youth in 26 European Member States (2012–2023): a longitudinal ecological study using repeated cross-sectional data

Current taxation and age-of-sale policies remain insufficient, with impacts varying by sex and region. Achieving the tobacco endgame requires harmonised EU-level measures and stronger enforcement, particularly of these two policies, to prevent the ongoing influx of new youth smoking initiates. This study suggests that their potential impact has been constrained by inadequate enforcement to date rather than by policy ineffectiveness.