[Series] Global HIV prevention is not on track: how a health systems approach can promote sustainable progress in African countries

The expansion of the global HIV response has led to substantial reductions in mortality and new infections over the past two decades. Yet, despite these gains, rates of new HIV infections remain much higher than projected, resulting in long-term consequences for controlling the epidemic. Challenges include siloed delivery approaches shaped by the demands and priorities of external funding, lack of integrated data systems for prevention, unaddressed structural risks, and limited community and multisectoral engagement.