[Comment] The future of HIV prevention in southeast Asia

HIV remains a public health threat globally, particularly in Asia and the Pacific, which was estimated to be home to 16·9% of 40·8 million people living with HIV worldwide in 2024.1 The region contributed 23·1% of all new HIV infections; however, of 8 million users of pre-exposure prophylaxis (PrEP) worldwide less than 5% live in Asia and the Pacific.2 Effective and sustainable implementation of prevention may prove challenging, but past experience and robust community-led approaches might pave the way for southeast Asia.