[Correspondence] Ferritin-guided iron supplementation in blood donors – Authors' reply

We thank Tomohiko Sato and colleagues for acknowledging the quality and relevance of our FORTE trial1 and for highlighting the importance of compliance to iron supplementation strategies, potential legal obstructions to prescribing supplements, and cultural and educational factors as international implementation challenges. Their reflections underscore the broader implications of our findings and the need to consider local contexts when translating research into practice. The ferritin-guided iron supplementation approach evaluated in FORTE offers a robust, scalable model that addresses methodological gaps, protects donor health, supports a sustainable blood supply, and limits unnecessary interventions.