[Comment] Advancing understanding of mature T-cell and natural killer-cell lymphomas

Mature T-cell and natural killer-cell lymphomas are rare, aggressive, and heterogenous malignancies, accounting for approximately 10–15% of non-Hodgkin lymphomas globally. Their striking geographic, ethnic, and molecular variations reflect the interplay between genetic predispositions, environmental exposures, and oncogenic drivers. For decades, outcomes have lagged behind those of aggressive B-cell lymphomas. This Series about mature T-cell and natural killer-cell lymphomas, published in The Lancet Regional Health—Western Pacific and The Lancet Haematology, offers a comprehensive, integrated perspective.