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Geriatrics/Aging
11th Mar, 2026
The New England Journal of Medicine
An 80-year-old woman was admitted to the hospital because of cough and hypoxemia (oxygen saturation, 83%). CT of the chest showed diffuse ground-glass opacities in both lungs. A diagnosis was made.
Emergency Medicine
The retina is a specialized patch of central nervous system tissue located at the back of the eye. When the principal source of oxygen and metabolic substrates to the retina — the central retinal artery — is occluded, rapid retinal cell death and loss of visual function ensue. This acute… The retina is a specialized patch of central nervous system tissue located at the back of the eye. When the principal source of oxygen and metabolic substrates to the retina — the central retinal artery — is occluded, rapid retinal cell death and loss of visual function ensue. This acute…
In acute central retinal artery occlusion treated within 4.5 hours after onset, intravenous tenecteplase did not result in greater recovery of vision at 30 days than aspirin and was associated with serious safety concerns.
After ischemic stroke, recurrence risk is reduced by identifying the stroke mechanism and targeting modifiable risk factors. Early diagnostic evaluation, prompt preventive therapy, and ongoing monitoring are central to care.
A 91-year-old man with a history of bladder carcinoma and left total knee arthroplasty was evaluated because of left knee pain. A culture of synovial fluid showed no growth. A diagnosis was made.
This feature about blood-pressure targets to manage hypertension offers a case vignette accompanied by two essays, one recommending a systolic blood-pressure target of less than 120 mm Hg and the other supporting a target of less than 140 mm Hg.
Pediatrics
When a mother cites the CDC as her source of dangerous misinformation about vaccines, her child’s pediatrician struggles: how hard can a doctor push back without destroying the trust built over a lifetime?
Both viral and host factors have contributed to the intensity of influenza activity during the 2025–2026 season. Some of these factors can be managed, whereas others are largely beyond human control.
Hematology/Oncology
When a physician’s own incidental finding sends her down a long and winding path to find answers, she finds herself overcome with worry — but also, eventually, a new appreciation for life.
Health Policy
The AHEAD model was intended to slow health care cost growth, improve population health, and advance health equity. But under the new administration, its focus has shifted from equity to efficiency.
Medical credit cards have emerged as a popular financing tool for patients seeking care they might otherwise be unable to afford. But these cards may ultimately increase financial burdens on patients.
The CMS Innovation Center is approaching the next negotiation cycle for the CGT Access Model. Several considerations will guide the selection of future candidate diseases and potential new model designs.
Psychiatry
A 27-year-old man with bipolar I disorder was admitted to the hospital with abnormal behaviors and confusion. Tachycardia was present, and the patient had a seizure. A diagnosis was made.
Gastroenterology
NOS host Lisa Rosenbaum and her guests lay bare the joys and rewards of full-spectrum primary care practice and consider ways of stoking students’ passion, and strengthening their ability, to pursue it.
After 60 years of cogitation about normal-pressure hydrocephalus, the results of a worthy randomized trial that assessed the effects of cerebrospinal fluid (CSF) shunting are now published in the Journal.1 No one seems to want to own idiopathic normal-pressure hydrocephalus. The symptoms are neurologic, the treatment…
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