Smart hydrogels act as 'micromachines' to squeeze and study living cells

Within tissues, cells are embedded in complex, three-dimensional structures known as the extracellular matrix. Their biomechanical interactions play a crucial role in numerous biological processes. Scientists at the Max Planck Institute for the Science of Light (MPL) have now developed a novel lab-on-a-chip system based on intelligent hydrogel structures, which enables precise pressure forces to be applied to cellular microenvironments.