SARS-CoV-2 peptide fragments selectively dysregulate specific immune cell populations via Gaussian curvature targeting

Proceedings of the National Academy of Sciences, Volume 123, Issue 2, January 2026. SignificancePrevious work has demonstrated that the proteome of SARS-CoV-2 can potentially be a rich source of AMP-like viral fragments, exemplars of which are associated with severe COVID-like inflammation in vitro and in vivo. Here, we demonstrate that …