Pegcetacoplan for Treatment of C3 Glomerulopathy and Immune-Complex MPGN

The kidney diseases C3 glomerulopathy and immune-complex membranoproliferative glomerulonephritis (MPGN), which are diagnosed through kidney biopsies in patients with evidence of glomerulopathy, have defied successful treatment. C3 glomerulopathy is a rare disease that encompasses C3 glomerulonephritis and dense-deposit disease. It is characterized on kidney biopsy by deposition of complement by-products,…