Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist for Obesity Treatment

11th Mar, 2026

Gastroenterology

The New England Journal of Medicine

In this phase 3, randomized trial, the use of orforglipron, an oral glucagon-like peptide-1 receptor agonist, led to significant mean body-weight reductions in patients with obesity, as compared with placebo.

Published By: The New England Journal of Medicine

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