Interprotomer communication and functional asymmetry in H/ACA snoRNPs

Proceedings of the National Academy of Sciences, Volume 122, Issue 51, December 2025. SignificanceH/ACA snoRNPs are critical for numerous RNA processes as they utilize different H/ACA snoRNAs to introduce pseudouridines in ribosomal and other noncoding RNAs as well as mRNAs. In addition, H/ACA snoRNPs stabilize and fold RNA thereby …