[In Context] Migraine as a dynamic continuum during the life course

Traditionally, migraine is defined by the occurrence of cycling episodes of headache and associated neurological symptoms, with a primary focus on the presence of a migraine episode at a specific point in time. However, emerging evidence suggests that migraine is a condition that extends across the life course, encompassing periods of remission, interictal states, and ongoing changes in disease activity. We propose a new perspective that considers migraine states across the life course. This broader view is essential for improving diagnosis, developing patient-centred care models, gaining deeper insights into the underlying pathophysiology, and understanding the interplay between migraine, its risk factors, and comorbidities.