[Editorial] Stopping Alzheimer's disease before symptoms start

Dementia due to Alzheimer's disease manifests years after the initial pathological changes in the brain. In fact, the deposition of amyloid plaques, and the subsequent tangles and neurodegeneration, can remain clinically silent for decades. This period presents a valuable opportunity for pharmacological treatments aimed at halting or delaying clinical manifestations. A Policy View in this issue explores initiatives that could soon facilitate the implementation of such treatments, at least in the USA.