[Correspondence] Population screening for Helicobacter pylori to reduce gastric cancer

We read Raghav Sundar and colleagues’ Seminar on gastric cancer with interest.1 The optimal approach to managing any disease with a burden as high as gastric cancer will probably be, where possible, primary prevention. As Sundar and colleagues correctly point out, gastric cancer is the fifth most common cancer worldwide.2 The International Agency for Research on Cancer (IARC) classified Helicobacter pylori as a human carcinogen more than 30 years ago,3 and there have been numerous randomised controlled trials (RCTs) of eradication therapy that have been conducted in populations at high risk of gastric cancer since the 1990s.