[Correspondence] Aligning SPIRIT and SAGER guidelines for equity in clinical trials

We welcome the revised Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) 2025 guidelines published in The Lancet and commend the efforts to enhance transparency and rigour in clinical trial protocols.1,2 Accurate and transparent reporting is fundamental to ensuring the validity of clinical trial findings, enhancing reproducibility and clarifying the generalisability of results across diverse populations.3 The updated SPIRIT guidelines introduce several important improvements, including clearer definitions of protocol contributors and strengthened guidance on data sharing and trial registration, which move us towards greater transparency and accountability in clinical research.