[Comment] Transdiagnostic prediction of serious mental disorders: opportunities and considerations

Both bipolar disorders and psychotic disorders are serious mental disorders that have a substantial effect on psychosocial functioning, quality of life, and life expectancy. Given that these disorders typically have onsets during late adolescence and early adulthood, they cause greatest effect at a time when young people are attempting to reach developmental milestones, and untreated psychosis or mood symptoms can disrupt educational and occupational goals. Thus, there is clear rationale and clinical need for earlier intervention, identifying those individuals at the greatest risk, and offering evidence-based treatments that might change the early progression of disorder, delaying—or optimally, preventing—the onset of the disorder.