[Comment] Towards sustainable relief in chronic low back pain

Non-specific low back pain remains one of the leading global causes of disability, substantially diminishing productivity and quality of life among working-age adults. A subset of individuals develop chronic non-specific low back pain, characterised by persistent functional limitations.1 This group accounts for a disproportionate share of health-care resource use compared with people experiencing acute or subacute episodes.2 When symptoms persist for longer than 12 weeks, neurophysiological adaptations can alter pain processing pathways, leading to a shift in the pain profile from predominantly nociceptive or neuropathic to nociplastic.