[Comment] Tick-borne viruses: moving the dial on diagnostics with diverse technological advances

Tick-borne viruses (TBVs) pose an escalating threat to human and animal health, driven by the geographical expansion of endemic pathogens (eg, tick-borne encephalitis virus) and continued spillover of emerging ones (eg, Yezo virus), many of which are associated with substantial morbidity and mortality (appendix pp 2–3).1–3 Multiroute transmission of TBVs, including tick bites and exposure to infected animal blood, tissues, or unpasteurised dairy in occupational settings (eg, slaughterhouses) and community contexts (eg, sacrificial religious gatherings), may obscure exposure history and hinder early clinical suspicion.