[Comment] NMDAR autoantibodies modify the phenotype of psychosis in severe brain inflammation

N-methyl-D-aspartate receptor (NMDAR) autoantibodies are of growing relevance in psychiatric research and practice, after their initial discovery in the context of NMDAR-antibody encephalitis. Because the course of this disease is clearly modifiable with immunotherapies, identifying its phenotypic characteristics is important. NMDAR-antibody encephalitis, involving affective-psychotic symptoms, and primary psychoses can occur in psychiatric settings and cause similar symptoms, but they require different diagnoses.