[Comment] More than medication

In The Lancet Psychiatry, Debora Zaccoletti and colleagues1 present a clinically meaningful and methodologically sound systematic review and meta-analysis comparing antidepressant deprescribing strategies in individuals with clinically remitted depression and anxiety. The authors’ thorough adherence to principles of scientific transparency gives much needed trustworthiness to analyses in a contested field. This work also provides a welcome and balanced contribution to the polarised debate around antidepressant discontinuation.