[Comment] Inclisiran for children: is it worth it?

Familial hypercholesterolaemia is one of the most common inherited metabolic disorders, with heterozygous familial hypercholesterolaemia (HeFH) affecting more than 30 million individuals worldwide, a quarter of whom are children. HeFH is characterised by markedly elevated LDL cholesterol concentrations from birth, resulting in a substantially increased lifetime risk of atherosclerotic cardiovascular disease (ASCVD).