[Comment] Hyperemesis gravidarum, perinatal depression, and the need for integrated maternal and infant care

Hyperemesis gravidarum affects 0·3–3·6% of women1 and is the leading cause of hospital admissions during the first trimester of pregnancy.2 Hyperemesis gravidarum is associated with serious consequences not only for the mother's physical health, but also for her mental health, particularly the risk of peripartum depression. Peripartum depression is recognised as the leading cause of illness during the perinatal period.3 Numerous studies have noted the existence of an association between hyperemesis gravidarum and depression; a meta-analysis by Mitchell-Jones and colleagues4 showed significantly higher depression scores in pregnant women with hyperemesis gravidarum than in controls without the disorder.