

In a systematic analysis for the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD), the GBD 2023 Headache Collaborators reinforce headache disorders as being one of the leading causes of non-fatal health loss, affecting nearly 2·9 billion individuals worldwide, with an age-standardised prevalence of 34·6% and causing 541·9 years lived with disability (YLDs) per 100 000 population.1 Migraine alone drives 90% of this burden, with females having a YLD rate more than twice that of males (739·9 vs 346·1 per 100 000).
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