[Comment] Clozapine: superior yet underused

In The Lancet Psychiatry, Jurjen J Luykx and colleagues compared the effectiveness of clozapine with other psychotropic drugs using nationwide register-based data from Finland and Sweden on nearly 20 000 individuals treated with clozapine.1 The primary outcome was psychiatric hospitalisation, and—with the exception of borderline personality disorder—the investigators found superiority of clozapine over other antipsychotics (and, in bipolar disorder, over other mood stabilisers) for all diagnoses examined.