[Articles] Diagnostic accuracy of low-complexity, manual nucleic acid amplification tests for the detection of pulmonary and extrapulmonary tuberculosis in adults and adolescents: a systematic review and meta-analysis∗

TB-LAMP has satisfactory performance for detecting pulmonary tuberculosis in adolescents and adults and is a potential alternative to molecular tests that require more advanced infrastructure. However, the inability to detect rifampicin resistance is an important limitation of TB-LAMP. Future research should focus on well powered studies to establish the diagnostic accuracy of TB-LAMP for extrapulmonary tuberculosis sites.