[Articles] Comparison of antidepressant deprescribing strategies in individuals with clinically remitted depression: a systematic review and network meta-analysis

In remitted depression, slow tapering plus psychological support is as effective as antidepressant continuation in preventing relapse and superior to abrupt or rapid discontinuation. In remitted anxiety, despite consistent population characteristics and effect estimates, limited evidence warrants cautious generalisation. Guidelines should promote individualised deprescribing with gradual tapering and structured psychological support.