An adipo-osteoprogenitor population in the endosteal niche contributes to bone and fat formation in adult mouse bone marrow

Proceedings of the National Academy of Sciences, Volume 122, Issue 47, November 2025. SignificanceBone health in adult individuals requires constant regeneration of new bone to replace the old tissue. With aging or various diseases, bone formation is diminished and the decline is often accompanied with increased marrow fat accumulation. …