[2025 Round-up] Major advances in traumatic brain injury research in 2025

2025 marked a turning point in traumatic brain injury (TBI) research, with studies now showing that TBI is a chronic condition characterised by prolonged biomarker elevations and long-term comorbidities, fundamentally shifting clinical management from acute intervention to lifelong monitoring and care. A new TBI classification framework was developed that captures the heterogeneity of TBI, which will allow for personalised treatment and targeted clinical trials. In parallel, emerging therapeutic approaches offer renewed hope for better outcomes.